Which resource contains TE codes to help guide generic substitution?

The resource that contains TE codes to aid in generic substitution is the Orange Book. The Orange Book, officially known as the "Approved Drug Products with Therapeutic Equivalence Evaluations," is published by the FDA and provides a comprehensive list of approved drug products alongside their therapeutic equivalence evaluations.

TE codes are important because they indicate whether a generic drug is considered therapeutically equivalent to its brand-name counterpart, which is crucial for pharmacists when deciding whether to substitute a prescribed medication with a generic version. A code 'A' indicates that the products are therapeutically equivalent, while a code 'B' suggests that they are not. By consulting the Orange Book, pharmacists can ensure that they are making safe and appropriate substitutions that align with pharmacy laws and regulations.

In contrast to the Orange Book, other resources like the Red Book and Pink Book serve different purposes, with the Red Book typically focusing on pricing and availability of prescription drugs and the Pink Book covering vaccine information. The Blue Book is less commonly referenced in this context and does not provide TE codes. Therefore, the Orange Book is the go-to resource for information on therapeutic equivalence in the realm of generic substitution.